Williams+Syndrome

** By: Lindsay Midgett, Kate Foley, Charlie Winters **
 * William’s Syndrome **

-Chromosome 7 -Caused by missing genes that produce elastin || -Usually occurs randomly, but small percentages inherit from parents -Single dominant Allele -Polygenic || -Not very common -Occurs in about 1 in 8,000 births || || -75% of people with this experience mental retardation - life threatening due to complications -feeding problems, growing and weight gaining problems -small, widely spaced teeth -delayed speech, development delay, ADD -excessively social Facial: -Small chin, full lips, small and upturned nose, puffy eyes, wide mouth Heart and Blood Vessel: -narrowing in the aorta or pulmonary blood vessels, increased heart rate, elevated calcium levels || -Avoid taking extra calcium and vitamin D - Treat high levels of blood calcium -Physical therapy available for joint stiffness -Speech and developmental therapy available for children -Other therapies available based off symptoms || -Prenatal testing is available (amniocentesis) - Blood pressure test - Blood test for missing chromosome -Echocardiography with Doppler ultrasound -Kidney ultrasound ||
 * ** Causes: ** || -Autosomal
 * ** What is the Pattern of Inheritance: ** || -Occurs during the formation of reproductive cells
 * ** Characteristics of the Disorder: ** || -Also known as Williams-Beuren Syndrome
 * ** Cont. of Characteristics: **
 * ** Treatments: ** || - No cure
 * ** Prevention: ** || -There is no known prevention for the genetic disorder causing Williams Syndrome ||
 * ** Testing: ** || yes:

[|http][|://][|www][|.][|nlm][|.][|nih][|.][|gov][|/][|medlineplus][|/][|ency][|/][|article][|/001116.][|htm] [|http][|://][|health][|.][|nytimes][|.][|com][|/][|health][|/][|guides][|/][|disease][|/][|williams][|-][|syndrome][|/][|overview][|.][|html] [|http][|://][|ghr][|.][|nlm][|.][|nih][|.][|gov][|/][|condition][|/][|williams][|-][|syndrome] [|http][|://][|www][|.][|thespeciallife][|.][|com][|/][|williams][|-][|syndrome][|.][|html]
 * References:**